#74 new
jakemiller

Influenza Virus Vaccine Development

Reported by jakemiller | December 29th, 2023 @ 07:32 AM

Amid the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause seasonal and cyclical pandemics with significant morbidity worldwide and mortality. According to the World Health Organization (WHO), seasonal influenza affects 5-10% of the global population each year, resulting in 3-5 million hospitalizations and approximately 500,000 deaths.

Types of Influenza Virus Vaccine Development Service
Influenza virus belongs to the Orthomyxoviridae family and comprise negative-sense, single stranded, segmented RNA genome. Influenza virus causes acute upper respiratory tract infection in patients and spreads rapidly through the air, causing periodic influenza pandemics around the world. There are four types of influenza viruses: A, B, C, and D. Influenza A virus (IAV) and B virus are clinically relevant to humans. IAVs can be further subdivided into 18 hemagglutinin (HA) and 11 neuraminidase (NA) subtypes based on the antigenic properties of surface glycoproteins. Most IAV subtypes exist in natural hosts (e.g., waterfowl, waterfowl, and other species), and only a few IAV subtypes infect humans. Because of the high mutation rate, IAV is difficult to predict, prevent or treat.

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