Influenza Virus Vaccine Development
Reported by jakemiller | December 29th, 2023 @ 07:32 AM
Amid the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause seasonal and cyclical pandemics with significant morbidity worldwide and mortality. According to the World Health Organization (WHO), seasonal influenza affects 5-10% of the global population each year, resulting in 3-5 million hospitalizations and approximately 500,000 deaths.
Types of
Influenza Virus Vaccine Development Service
Influenza virus belongs to the Orthomyxoviridae family and comprise
negative-sense, single stranded, segmented RNA genome. Influenza
virus causes acute upper respiratory tract infection in patients
and spreads rapidly through the air, causing periodic influenza
pandemics around the world. There are four types of influenza
viruses: A, B, C, and D. Influenza A virus (IAV) and B virus are
clinically relevant to humans. IAVs can be further subdivided into
18 hemagglutinin (HA) and 11 neuraminidase (NA) subtypes based on
the antigenic properties of surface glycoproteins. Most IAV
subtypes exist in natural hosts (e.g., waterfowl, waterfowl, and
other species), and only a few IAV subtypes infect humans. Because
of the high mutation rate, IAV is difficult to predict, prevent or
treat.
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