Replication-Competent Virus Testing
Reported by Marcia Brady | August 23rd, 2024 @ 09:13 AM
Recombinant viruses are especially useful for gene transfer and protein expression in vivo and in vitro. During viral vector production, particles may be generated which are replication competent through recombination with host sequences or by contamination. The probability of producing replication competent virus, although low, increases with each successive amplification. Therefore, development of a sensitive assay for detection of replication-competent recombinant viruses in large-scale vector preparations is needed.
No comments found
Please Sign in or create a free account to add a new ticket.
With your very own profile, you can contribute to projects, track your activity, watch tickets, receive and update tickets through your email and much more.
Create new ticket
Create your profile
Help contribute to this project by taking a few moments to create your personal profile. Create your profile ยป
Marcia Brady