
L-α-phosphatidylcholine
Reported by cailynn johnson | January 16th, 2024 @ 06:10 AM
Phosphatidylcholine (PC) was first found in egg yolk and thus is also known as “lecithin”. It is the most abundant phospholipid component of all mammalian cell biological membranes. PC generally comprises 40-50% of total cellular phospholipids, even though membranes of different cell types, individual organelles, or even the two leaflets of organelle consist of distinct phospholipid compositions, PC has a cylindrical shape due to the similar in width of polar head and the hydrophobic tail, such shape tends to form monolayers that are flat or almost flat. Lysophosphatidylcholine (LPC) is one-tailed lipid modeled as an inverted cone, hence, has a positive spontaneous curvature and tends to form micelle with the polar head directed outward.
As a leader in the field of lipid-based drug delivery, Creative Biolabs has years of experience in lipid-based carrier development. We can provide custom synthesized lipid as you need.
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