Lactic Acid Bacteria System
Reported by Marcia Brady | February 6th, 2024 @ 08:04 AM
Lactic acid bacteria (LAB) are considered potential candidates as mucosal vaccine vectors. One major advantage of recombinant LAB strains as delivery vehicles for vaccines is their potential to elicit specific systemic and mucosal immune responses against selected antigens. One vaccine is Whole-Cell LAB-Based Vaccines that express the receptor binding domain (RBD) of the SARS-CoV-2. The spike (S) protein of coronaviruses mediates receptor binding and membrane fusion and is crucial for determining host tropism and transmission capacity.
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