Ion Channel Screening
Reported by Marcia Brady | February 6th, 2024 @ 08:02 AM
Ion channels continue to be an important therapeutic target for a range of indications such as hypertension, arrhythmia, pain, stroke, epilepsy, depression, diabetes, local anesthesia, bipolar disorder, COPD, and autoimmune disorders. Ion channels are not only important drug targets, but also play an important role in drug safety evaluation. Many drugs withdrawn from the market due to cardiac-related side effects have been shown to block the human ether-a-go-go (hERG) ion channel, delaying repolarization of the cardiac action potential and possibly leading to a potentially fatal arrhythmia.
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Marcia Brady